Clinical Research Trials
We understand that choosing to participate in a clinical trial is a very important decision that involves not only the patient, but their family, friends, and primary care physicians as well. All infertility physicians at the University of Oklahoma share the common goal of conducting clinical research and are dedicated to providing comprehensive care for their patients struggling with infertility.
If you have any questions or would like further information about participating in a clinical trial, please call OU Physicians Reproductive Medicine Research at 405-271-1615.
Multi-center, parallel group, randomized controlled trial of modified natural versus programmed cycles for frozen embryo transfers and their association with preeclampsia and live births (NatPro)
NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent). Each participant will have up to 3 FET cycles until live birth occurs, or the participant has no embryos available for transfer. The central hypothesis is that pregnancy resulting from a modified natural cycle FET will have a lower proportion of preeclampsia compared to that of a programmed FET
Evaluating the relationship between ovarian reserve and facial age as determined by computer software in non-infertile population
To determine whether facial age is better correlated to anti-mullerian hormone than a woman’s chronological age. We will look at serum anti-mullerian hormone level, which participants will have drawn at the OU Physicians Reproductive Medicine Clinic. The patients will also complete a survey and have their photos taken on a tablet the day their blood is drawn. This facial image will be sent without any other patient identifiers to be analyzed by the artificial intelligence enhanced automated face age solutions. Participating subjects will receive the data collected.
Myo-inositol as an Adjuvant to Letrozole for Infertility in Polycystic Ovary Syndrome (MALI-PCOS): a randomized pilot trial
This will be a prospective, double-blind randomized clinical trial of letrozole and placebo vs letrozole and inositols for up to 5 treatment cycles (spanning approximately 24 weeks) of ovulation induction or until pregnancy is achieved. Subjects will be provided the supplement, Femara and progesterone blood testing as part of their participation.
A Prospective, Multicenter, Single-arm, Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue under ULTRAsound Visualization in Women with Infertility due to Polycystic Ovary Syndrome “ULTRA-US” Study
May Health is developing an innovative treatment designed to restore ovulation.
Through targeted ovarian ablation, this one-time treatment aims to lower androgen production, which can often restore ovulation. Ovarian Rebalancing™ can be done conveniently at the physician’s office–no hormones necessary.
